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Cat. No.: HY-120340

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nNOS-IN-7

nNOS-IN-7 is a selective nNOS inhibitor with a K_i value of 0.049 μM against rat nNOS. nNOS-IN-7 is applicable to the research of neurodegenerative diseases.

For research use only. We do not sell to patients.

CAS No.: 1895092-16-6
Formula: C₂₁H₂₂N₄
Molecular Weight:330.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

nNOS-IN-7 Chemical Structure

CAS No.: 1895092-16-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

nNOS-IN-7 is a selective nNOS inhibitor with a K_i value of 0.049 μM against rat nNOS. nNOS-IN-7 is applicable to the research of neurodegenerative diseases^[1].

IC₅₀ & Target^[1]

nNOS

0.049 μM (Ki)

iNOS

44 μM (Ki)

eNOS

11.16 μM (Ki)

All NO Synthase Isoforms :

In Vitro

nNOS-IN-7 (Compound 7) inhibits NOS, with K_i values of 0.049, 44, and 11.16 μM for nNOS, iNOS, and eNOS, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1895092-16-6
Molecular Weight 330.44
Formula C₂₁H₂₂N₄
SMILES

N#CC1=CC=C(C=C1C)CCNCC=2C=CC=3C(=NC(N)=CC3C)C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Richard B. Silverman, et al. 2-Aminoquinoline-Based Compounds for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition. US20160368877A1. United States. 2016-08-31.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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nNOS-IN-7

All NO Synthase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

nNOS-IN-7 Related Classifications

HY-120340 Related Classifications