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Cat. No.: HY-186285

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NO donor-1

NO donor-1 is a diol diazeniumdiolate-based Nitric oxide donor.

For research use only. We do not sell to patients.

CAS No.: 1469888-67-2
Formula: C₁₃H₁₈N₄O₄
Molecular Weight:294.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NO donor-1 Chemical Structure

CAS No.: 1469888-67-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

NO donor-1 is a diol diazeniumdiolate-based Nitric oxide donor^[1].

All NO Synthase Isoforms :

In Vitro

NO donor-1 (Compound 4a) exhibits a nitric oxide release half-life of 8.3 minutes in pH 7.4 buffer^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1469888-67-2
Molecular Weight 294.31
Formula C₁₃H₁₈N₄O₄
SMILES

[O-][N+](C1=CC=C(CO/N=[N+](N2CCCCC2C)\[O-])C=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sharma K, et al. Nitroreductase-activated nitric oxide (NO) prodrugs. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5964-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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NO donor-1

All NO Synthase Isoforms