NS5A-IN-4
NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a. NS5A-IN-4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 2088243-03-0
- Formula: C47H48N8O6
- Molecular Weight:820.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1.2 pM (gT1b), 4.6 pM (gT2a), 10.3 pM (gT4a), 362 pM (gT3a), 693 pM (gT5a), 2296 pM (gT1a)[1]
Chemical Information
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CAS No. 2088243-03-0
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Molecular Weight 820.93
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Formula C47H48N8O6
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SMILES
COC(N[C@@H](C(C)C)C(N1[C@H](C2=NC=C(C3=CC(C4=CC=CC=C4)=C(C=C3)C#CC#CC5=CN=C([C@H]6N(CCC6)C([C@@H](C7=CC=CC=C7)NC(OC)=O)=O)N5)N2)CCC1)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)