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Cat. No.: HY-76409

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Otamixaban hydrochloride

(Synonyms: FXV673 hydrochloride)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (K_i=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa.

For research use only. We do not sell to patients.

CAS No.: 409081-12-5
Formula: C₂₅H₂₇ClN₄O₄
Molecular Weight:482.96

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Otamixaban hydrochloride Chemical Structure

CAS No.: 409081-12-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Clinical Trial
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (K_i=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa^[1].

IC₅₀ & Target

IC50: Factor Xa^[1]

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 409081-12-5
Appearance Solid
Molecular Weight 482.96
Formula C₂₅H₂₇ClN₄O₄
Color Light yellow to yellow
SMILES

N=C(N)C1=CC=CC(C[C@@H](C(OC)=O)[C@@H](C)NC(C2=CC=C(C3=CC=[N+]([O-])C=C3)C=C2)=O)=C1.Cl
Synonyms

FXV673 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Journal Impact Factor

Elife

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry. [Abstract]

2022 Mar 23:11:e77444. PMID: 35294338

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eikelboom JW, Weitz JI.Otamixaban in acute coronary syndromes.Lancet. 2009 Sep 5;374(9692):762-4. Epub 2009 Aug 28. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Otamixaban hydrochloride

1 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
- Clinical Trial
Chemical Information
Publications (1)
Purity & Documentation
References

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Otamixaban hydrochloride

Publications Citing Use of MedChemExpress (MCE) Otamixaban hydrochloride

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

Otamixaban hydrochloride Related Classifications

HY-76409 Related Classifications