P2X3 antagonist 40
P2X3 antagonist 40 is a P2X3 antagonist with a human P2X3 receptor pIC50 < 4.52. P2X3 antagonist 40 can be used for research on ATP-mediated proinflammatory fingerprint, including overactive bladder, pain, and chronic cough.
For research use only. We do not sell to patients.
- Formula: C24H19F3N4O2S
- Molecular Weight:484.49
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All P2X Receptor Isoforms
More
Biological Activity
|
P2X2 Receptor <4.52 (pIC50) |
P2X3 antagonist 40 (11) shows no measurable inhibitory activity against α,β-meATP-induced currents in HEK293 cells overexpressing human P2X3 receptor, with a pIC50 < 4.52[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 484.49
-
Formula C24H19F3N4O2S
-
SMILES
FC(C1=CC=C([C@H](NC(C2=C(C3=CC=CC=C3)SC(C4=NC=C(C)C=C4)=N2)=O)C)C=[N+]1[O-])(F)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)