P2Y14 antagonist 1
P2Y14 antagonist 1 (compound 45) is a high selective and orally active P2Y14R antagonist with an IC50 of 0.70 nM. P2Y14R antagonist 1 demonstrates significant anti-inflammatory efficacy, effectively mitigating the pulmonary infiltration of immune cells and inflammatory response through suppressing the NLRP3 signaling pathway. P2Y14R antagonist 1 has the potential for the research of acute lung injury.
For research use only. We do not sell to patients.
- Formula: C24H21N3O3
- Molecular Weight:399.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All P2Y Receptor Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 399.44
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Formula C24H21N3O3
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SMILES
O=C(NC1=CC(C2=NC3=C(N2)C=CC=C3)=CC(C(OC)=O)=C1)CC4=CC=C(C=C4)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)