1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. PD-1-IN-22

PD-1-IN-22 

Cat. No.: HY-128605
Handling Instructions

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM.

For research use only. We do not sell to patients.

PD-1-IN-22 Chemical Structure

PD-1-IN-22 Chemical Structure

CAS No. : 2349372-98-9

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Description

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1].

IC50 & Target

IC50: 92.3 nM (programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction)[1]

In Vitro

PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells[1].

Molecular Weight

459.50

Formula

C₂₅H₂₅N₅O₄

CAS No.

2349372-98-9

SMILES

CC1=C(NC(C2=CC(CNCCO)=CN3C2=NN=C3)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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PD-1-IN-22
Cat. No.:
HY-128605
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