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Cat. No.: HY-183860

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Pefabloc PL

Pefabloc PL is a plasmin inhibitor with submicromolar-range inhibitory activity against the trypsin-like serine protease plasmin.

For research use only. We do not sell to patients.

CAS No.: 2131171-67-8
Formula: C₃₁H₃₃N₅O₄S₂
Molecular Weight:603.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pefabloc PL Chemical Structure

CAS No.: 2131171-67-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Pefabloc PL is a plasmin inhibitor with submicromolar-range inhibitory activity against the trypsin-like serine protease plasmin^[1].

In Vitro

Pefabloc PL (compound 70) exerts inhibitory effects against plasmin, uPA and plasma kallikrein^[1].
Pefabloc PL inhibits multiple trypsin-type serine proteases at submicromolar level^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2131171-67-8
Molecular Weight 603.75
Formula C₃₁H₃₃N₅O₄S₂
SMILES

O=C(N1CC(CCC1)C(NCC2=CC=CS2)=O)[C@@H](NS(=O)(C3=CC4=C(C=CC=C4)C=C3)=O)CC5=CC(C(N)=N)=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Steinmetzer T, et al. Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding. J Med Chem. 2020;63(4):1445-1472. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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