Pibrentasvir-d6
Pibrentasvir-d6 (ABT-530-d6) is the deuterium labeled Pibrentasvir (HY-101662). Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.
For research use only. We do not sell to patients.
- Formula: C57H59D6F5N10O8
- Molecular Weight:1119.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1353900-92-1
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Molecular Weight 1119.22
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Formula C57H59D6F5N10O8
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SMILES
FC(C=C(N=C([C@H](CCC1)N1C([C@H]([C@@H](C)OC)NC(OC([2H])([2H])[2H])=O)=O)N2)C2=C3)=C3[C@@H]4N(C5=CC(F)=C(N6CCC(C7=CC=C(F)C=C7)CC6)C(F)=C5)[C@@H](C(C=C(NC([C@H](CCC8)N8C([C@H]([C@@H](C)OC)NC(OC([2H])([2H])[2H])=O)=O)=N9)C9=C%10)=C%10F)CC4
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Synonyms
ABT-530-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)