Pim-1 kinase inhibitor 11
Pim-1 kinase inhibitor 11 (10f) is a PIM-1 inhibitor, with an IC50 of 0.18 μM. Pim-1 kinase inhibitor 11 (10f) exhibits anticancer activity. Pim-1 kinase inhibitor 11 (10f) induces apoptosis and arrests cell cycle progression.
For research use only. We do not sell to patients.
- Formula: C27H20N4O
- Molecular Weight:416.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PIM1 0.18 μM (IC50) |
Pim-1 kinase inhibitor 11 (10f) demonstrates notable anticancer properties, particularly against A-549 lung cancer cells (IC50 range: 1.28-3.52 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 416.47
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Formula C27H20N4O
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SMILES
COC(C=C1)=CC=C1C2=CC=NC3=C2C(C4=CNC5=C4C=CC=C5)=NN3C6=CC=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)