country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-159095

Copy Link Print Information

PKR activator 5

PKR activator 5 (Compound 18) is an activator for pyruvate kinase R (PKR) with an AC₅₀ of 28 nM.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2761226-35-9
Fòrmula: C₂₃H₁₉ClFN₉O
Peso molecular:491.91

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

PKR activator 5 Chemical Structure

No. CAS: 2761226-35-9

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

PKR activator 5 (Compound 18) is an activator for pyruvate kinase R (PKR) with an AC₅₀ of 28 nM^[1].

IC₅₀ & Target

AC₅₀: 28 nM (PKR)

Chemical Information

No. CAS 2761226-35-9
Peso molecular 491.91
Fòrmula C₂₃H₁₉ClFN₉O
SMILES

CC1=NN(C(CNC(NCC2=NC=NN2C3=CC4=C(C=C3)C=CC=N4)=O)=N1)C5=CC=C(C(F)=C5)Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yu C, et al., The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead series. Bioorg Med Chem Lett. 2024 Jun 29;110:129865. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto