PMO-G
PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy.
For research use only. We do not sell to patients.
- CAS No.: 2708274-72-8
- Formula: C43H46ClN8O7P
- Molecular Weight:853.30
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2708274-72-8
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Appearance Solid
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Molecular Weight 853.30
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Formula C43H46ClN8O7P
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Color White to light yellow
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SMILES
CN(C)P(OC[C@H](C1)O[C@@H](N2C3=NC(NC(C(C)C)=O)=NC(OCCC4=CC=C(C=C4)[N+]([O-])=O)=C3N=C2)CN1C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. An, J. Y., et al., (2020). Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy. Nanoscale research letters, 15(1), 133. [Content Brief]
[2]. Lin, C., et al., (2020). Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle. Molecular therapy : the journal of the American Society of Gene Therapy, 28(5), 1339–1358. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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