2. Others Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Biochemical Assay Reagents Environmental Pollutants P-glycoprotein Creatine Kinase
  4. Poloxamer 403 (P123)

Poloxamer 403 (P123)  (Synonyms: PEG-PPG-PEG, 5750 (Average))

Cat. No.: HY-D1005A25
COA
SDS
Handling Instructions Technical Support

Poloxamer 403 P123 is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 5750. Poloxamer has the ability to inhibit P-gp. Poloxamer 403 increases creatine kinase levels. Poloxamer 403 is myotoxic.

For research use only. We do not sell to patients.

Poloxamer 403 (P123)

Poloxamer 403 (P123) Chemical Structure

CAS No. : 9003-11-6

Size Price Stock Quantity
Solvent
10 mL In-stock
Solvent
25 mL In-stock
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Based on 1 publication(s) in Google Scholar

Poloxamer 403 (P123) Related Antibodies

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Description

Poloxamer 403 P123 is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 5750. Poloxamer has the ability to inhibit P-gp. Poloxamer 403 increases creatine kinase levels. Poloxamer 403 is myotoxic[1][2].

In Vitro

Poloxamer 403 can be used as a cosmetic ingredient[1].
Poloxamer has the ability to inhibit P-gp[2].
Poloxamer has been proposed as an agent carrier to improve agent efficacy and reduce side effects[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Poloxamer 403 (P123) Related Antibodies
In Vivo

Poloxamer 403 (25% (w/w); i.m.) produces marked muscle damage and increases CPK levels in New Zealand white rabbits[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

5750 (Average)

CAS No.
Appearance

<50°C Solid,>52°C Liquid

Color

Colorless to off-white

SMILES

[Poloxamer 403 (P123)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool
Purity & Documentation

SDS (252 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References
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Poloxamer 403 (P123) Related Classifications

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The dilution calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Poloxamer 403 (P123)9003-11-6PEG-PPG-PEG, 5750 (Average)Biochemical Assay ReagentsEnvironmental PollutantsP-glycoproteinCreatine KinaseEnvironmental ContaminantsP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243CKpolymerInhibitorinhibitorinhibit

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