PROTAC Bcl-xL degrader-3
PROTAC Bcl-xL degrader-3 is a potent PROTAC Bcl-xL degrader. PROTAC Bcl-xL degrader-3 forms ternary complexes with the VHL-complex and BCL-XL. PROTAC Bcl-xL degrader-3 can be used in research on acute lymphoblastic leukemia.
(Pink: Bcl-xL ligand (HY-185551); Blue: VHL ligand (HY-112078); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 2471970-60-0
- Formula: C82H105ClF3N11O11S4
- Molecular Weight:1641.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
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Bcl-xL |
VHL |
Chemical Information
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CAS No. 2471970-60-0
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Molecular Weight 1641.49
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Formula C82H105ClF3N11O11S4
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SMILES
O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCCCCCC(N(CC4)CCN4C[C@@](C)(C5)CCC(C6=CC=C(C=C6)Cl)=C5CN7CCN(C8=CC=C(C=C8)C(NS(=O)(C9=CC(S(C(F)(F)F)(=O)=O)=C(C=C9)N[C@@H](CSC%10=CC=CC=C%10)CCN%11CCOCC%11)=O)=O)CC7)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)