1. PROTAC Apoptosis
  2. PROTACs Bcl-2 Family
  3. PROTAC Bcl-xL degrader-3

PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44).

For research use only. We do not sell to patients.

PROTAC Bcl-xL degrader-3 Chemical Structure

PROTAC Bcl-xL degrader-3 Chemical Structure

CAS No. : 2471970-60-0

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Based on 1 publication(s) in Google Scholar

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Description

PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44)[1].

IC50 & Target[1]

Bcl-xL

 

VHL

 

Molecular Weight

1641.49

Formula

C82H105ClF3N11O11S4

CAS No.
SMILES

O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCCCCCC(N(CC4)CCN4C[C@@](C)(C5)CCC(C6=CC=C(C=C6)Cl)=C5CN7CCN(C8=CC=C(C=C8)C(NS(=O)(C9=CC(S(C(F)(F)F)(=O)=O)=C(C=C9)N[C@@H](CSC%10=CC=CC=C%10)CCN%11CCOCC%11)=O)=O)CC7)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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PROTAC Bcl-xL degrader-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PROTAC Bcl-xL degrader-3
Cat. No.:
HY-132997
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