BCL-xL ligand 3
BCL-xL ligand 3 is a BCL-xL PROTAC ligand. BCL-xL ligand 3 can be conjugated with E3 ligase Ligand (HY-112078) and linker to synthesize PROTAC Bcl-xL degrader-3 (HY-132997).
For research use only. We do not sell to patients.
- CAS No.: 3053404-37-5
- Formula: C51H63ClF3N7O6S3
- Molecular Weight:1058.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Bcl-xL |
A PROTAC consists of two distinct ligands linked by a linker: one is a ligand for an E3 ubiquitin ligase, and the other is a ligand for a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3053404-37-5
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Molecular Weight 1058.73
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Formula C51H63ClF3N7O6S3
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SMILES
C[C@](CN1CCNCC1)(C2)CCC(C3=CC=C(C=C3)Cl)=C2CN4CCN(C5=CC=C(C=C5)C(NS(=O)(C6=CC(S(C(F)(F)F)(=O)=O)=C(C=C6)N[C@@H](CSC7=CC=CC=C7)CCN8CCOCC8)=O)=O)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)