3053404-37-5
Chemical Structure
BCL-xL ligand 3
- CAS No.: 3053404-37-5
- Formula:C51H63ClF3N7O6S3
- Molecular Weight:1058.73
InChIKey: JVYARBBCGYHVQD-MKVVGXHPSA-N
SMILES: C[C@](CN1CCNCC1)(C2)CCC(C3=CC=C(C=C3)Cl)=C2CN4CCN(C5=CC=C(C=C5)C(NS(=O)(C6=CC(S(C(F)(F)F)(=O)=O)=C(C=C6)N[C@@H](CSC7=CC=CC=C7)CCN8CCOCC8)=O)=O)CC4
Biological Activity: BCL-xL ligand 3 is a BCL-xL PROTAC ligand. BCL-xL ligand 3 can be conjugated with E3 ligase Ligand (HY-112078) and linker to synthesize PROTAC Bcl-xL degrader-3 (HY-132997)[1].
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BCL-xL ligand 3 | BCL-xL ligand 3 is a BCL-xL PROTAC ligand. BCL-xL ligand 3 can be conjugated with E3 ligase Ligand (HY-112078) and linker to synthesize PROTAC Bcl-xL degrader-3 (HY-132997). | |||||||||||||||||||||
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Keywords