2. JAK/STAT Signaling PROTAC Protein Tyrosine Kinase/RTK
  3. EGFR PROTACs
  4. PROTAC EGFR degrader 8

PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC.

For research use only. We do not sell to patients.

PROTAC EGFR degrader 8 Chemical Structure

PROTAC EGFR degrader 8 Chemical Structure

CAS No. : 2925923-46-0

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PROTAC EGFR degrader 8 Related Antibodies

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Description

PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].

Molecular Weight

796.32

Formula

C40H46ClN11O5
CAS No.
SMILES

O=C(C1=C(NC2=NC(NC3=CC=C(N4CCN(CC4)C(CN5CCN(CC5)C6=CC=C(NC7C(NC(CC7)=O)=O)C=C6)=O)C=C3OC)=NC=C2Cl)C=CC=C1)NC
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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PROTAC EGFR degrader 8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC EGFR degrader 82925923-46-0PROTAC EGFR degrader8PROTAC EGFR degrader-8EGFRPROTACsEpidermal growth factor receptorErbB-1HER1CancerNSCLCH1975PC-9HCC827Inhibitorinhibitorinhibit

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