2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. PROTAC PTK6 ligand-1

PROTAC PTK6 ligand-1 is an intermediate for BTK kinase inhibitor preparation. PROTAC PTK6 ligand-1 can be used in the synthesis of ARD-61 (HY-139659).

For research use only. We do not sell to patients.

PROTAC PTK6 ligand-1 Chemical Structure

PROTAC PTK6 ligand-1 Chemical Structure

CAS No. : 2408341-98-8

Size Price Stock Quantity
1 mg USD 350 In-stock
5 mg USD 1190 In-stock
10 mg USD 1910 In-stock
25 mg USD 4020 In-stock
50 mg USD 6430 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

PROTAC PTK6 ligand-1 Related Antibodies

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Description

PROTAC PTK6 ligand-1 is an intermediate for BTK kinase inhibitor preparation[1]. PROTAC PTK6 ligand-1 can be used in the synthesis of ARD-61 (HY-139659)[2].

Molecular Weight

540.63

Formula

C27H32N4O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)[C@H](C1=CC(C)=NO1)C(N2[C@@H](C[C@H](C2)O)C(N[C@H](C3=CC=C(C4=C(N=CS4)C)C=C3)CC(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (184.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8497 mL 9.2485 mL 18.4969 mL
5 mM 0.3699 mL 1.8497 mL 3.6994 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8497 mL 9.2485 mL 18.4969 mL 46.2423 mL
5 mM 0.3699 mL 1.8497 mL 3.6994 mL 9.2485 mL
10 mM 0.1850 mL 0.9248 mL 1.8497 mL 4.6242 mL
15 mM 0.1233 mL 0.6166 mL 1.2331 mL 3.0828 mL
20 mM 0.0925 mL 0.4624 mL 0.9248 mL 2.3121 mL
25 mM 0.0740 mL 0.3699 mL 0.7399 mL 1.8497 mL
30 mM 0.0617 mL 0.3083 mL 0.6166 mL 1.5414 mL
40 mM 0.0462 mL 0.2312 mL 0.4624 mL 1.1561 mL
50 mM 0.0370 mL 0.1850 mL 0.3699 mL 0.9248 mL
60 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.7707 mL
80 mM 0.0231 mL 0.1156 mL 0.2312 mL 0.5780 mL
100 mM 0.0185 mL 0.0925 mL 0.1850 mL 0.4624 mL
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PROTAC PTK6 ligand-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC PTK6 ligand-12408341-98-8Ligands for Target Protein for PROTACTarget Protein-binding MoietyintermediateBTK kinaseInhibitorinhibitorinhibit

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