PXK/Slob
PXK (the counterpart of Drosophila Slob) is a modular protein that fuses an N-terminal PX domain, a kinase-like pseudokinase domain, and a C-terminal region related to binding partners of ion pumps. The PX domain mediates membrane association, while the protein binds the Na,K-ATPase beta-subunit and modulates its trafficking and pumping activity, echoing the role of fly Slob in regulating the Slowpoke BK potassium channel. Catalytic kinase function for PXK has not been established; it appears to act primarily as a scaffold at membranes. Recombinant PXK supports studies of ion-transport regulation, PX-domain membrane targeting, and pseudokinase scaffolding.
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PXK/Slob Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
