PXK Protein, Human (Sf9, His, GST)

PXK protein binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3, indicating a potential role in regulating neural electrical excitability and synaptic transmission. Despite lacking kinase activity, PXK's interaction with these subunits suggests a regulatory function in neural processes, emphasizing its potential contribution to the complex mechanisms governing brain neuronal function and communication. PXK Protein, Human (Sf9, His, GST) is the recombinant human-derived PXK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PXK Protein, Human (Sf9, His, GST) is 577 a.a., .

PXK protein exhibits binding affinity for and modulation of brain Na,K-ATPase subunits ATP1B1 and ATP1B3, potentially playing a crucial role in the regulation of electrical excitability and synaptic transmission within the brain. While its precise molecular function may not involve kinase activity, its interaction with these Na,K-ATPase subunits suggests a regulatory role in neural processes, highlighting PXK as a potential contributor to the intricate mechanisms governing neuronal function and communication in the brain.

Human

Sf9 insect cells

N-8*His;N-GST

Q7Z7A4 (A2-G578)

54899

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.