Serpin A3C
Serpin A3C belongs to the SERPINA3 cluster of closely related serpin genes on human chromosome 14 and was formerly described as an antichymotrypsin-like protein. It is a secreted glycoprotein whose reactive center loop inhibits chymotrypsin-like serine proteases, with documented activity against cathepsin G and mast cell chymase. Expression is highest in lung and heart and is induced by inflammatory stimuli, positioning A3C at mucosal and vascular sites where neutrophil and mast cell proteases are released. Because of extensive homology within the A3 cluster, recombinant A3C is valuable for isoform-specific antibody validation and for dissecting the individual protease targets of cluster members.
-
Serpin A3C Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
