Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei

  • Phytochemistry. 2001 Oct;58(4):627-9. doi: 10.1016/s0031-9422(01)00248-5.
X C Li  1 ,  D C Dunbar ,  H N ElSohly ,  L A Walker ,  A M Clark
Affiliations
  • 1. National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, USA.
PMID: 11576612 DOI: 10.1016/s0031-9422(01)00248-5
Abstract

The indolopyridoquinazoline alkaloid, 3-hydoxyrutaecarpine, was isolated from Leptothyrsa sprucei, along with 8-methoxypsoralen, 5-methoxypsoralen, imperatorin, isoimperatorin, kaempferol 3-O-alpha-L-rhamnopyranoside, clematine and cnidioside B. The usefulness of the gradient 1H-15N HMBC NMR spectroscopy in the structure elucidation of 3-hydroxyrutaecarpine is noted.

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