Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans

  • J Nat Prod. 1992 Aug;55(8):1145-8. doi: 10.1021/np50086a019.
M C Breschi  1 ,  E Martinotti ,  S Catalano ,  G Flamini ,  I Morelli ,  A M Pagni
Affiliations
  • 1. Istituto Policattedra di Discipline Biologiche, Facoltà di Farmacia, Università di Pisa, Italy.
PMID: 1431938 DOI: 10.1021/np50086a019
Abstract

The traditional therapeutic indications for the use of Ajuga reptans (Labiatae) have been investigated. The H2O-soluble part of a crude and partially purified MeOH extract and two isolated Iridoids (8-O-acetylharpagide and harpagide), were tested for a biological activity on isolated smooth muscle preparations from guinea pig.

Products