Structure of lasiansine from Aconitumnagarum var. lasiandrum

  • J Asian Nat Prod Res. 2006 Oct-Nov;8(7):619-24. doi: 10.1080/10286020500208550.
H Ji  1 F-P Wang
Affiliations
  • 1. Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu, 610041, China.
Abstract

A new C19-diterpenoid alkaloid, lasiansine (1), was isolated from the roots of Aconitu nagarum var. lasiandrum (Ranunculaceae) together with six known diterpenoid Alkaloids. The structure of 1 was elucidated by spectral methods (1H-NMR, 13C-NMR, 2D-NMR, HRMS, IR), and the 13C-NMR spectrum of 16-epipyroaconine (3) and the single-crystal X-ray analysis of its derivative (5) are reported for the first time.

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