Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana

  • Planta Med. 2008 Feb;74(2):171-4. doi: 10.1055/s-2008-1034278.
Jesús G Díaz  1 ,  Armando J Carmona ,  Fernando Torres ,  José Quintana ,  Francisco Estévez ,  Werner Herz
Affiliations
  • 1. Instituto Universitario de Bio-Orgánica Antonio González, La Laguna, Tenerife, Spain.
PMID: 18214815 DOI: 10.1055/s-2008-1034278
Abstract

The Flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.

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