Kaempferol tetraacetate
Kaempferol tetraacetate (AF33) is a natural product. Kaempferol tetraacetate shows cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 16274-11-6
- Formula: C23H18O10
- Molecular Weight:454.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
40.7 μM
Compound: 16
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Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay
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[PMID: 25659770] |
| J774.2 | IC50 |
15.56 μM
Compound: 1a
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Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay
Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay
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[PMID: 19489596] |
Kaempferol tetraacetate (compound 1a) (0-100 µM; 72 h) shows cytotoxicity with IC50s of 45, 48, 37 µM for HL-60, U937, SK-MEL-1 cells, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HL-60, U937, SK-MEL-1 cells
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Concentration:0-100 µM
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Incubation Time:72 h
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Result:Showed cytotoxicity with IC50s of 45, 48, 37 µM for HL-60, U937, SK-MEL-1 cells, respectively.
Chemical Information
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CAS No. 16274-11-6
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Molecular Weight 454.38
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Formula C23H18O10
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SMILES
CC(OC1=C2C(OC(C3=CC=C(OC(C)=O)C=C3)=C(OC(C)=O)C2=O)=CC(OC(C)=O)=C1)=O
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Synonyms
AF33
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mei Q, et al. Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates. Beilstein J Org Chem. 2015 Feb 25;11:288-93. [Content Brief]
[2]. Díaz JG, et al. Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana. Planta Med. 2008 Feb;74(2):171-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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