Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB

  • Clin Infect Dis. 2009 Mar 1;48(5):e50-2. doi: 10.1086/597010.
Edward D Chan  1 ,  Matthew J Strand ,  Michael D Iseman
Affiliations
  • 1. Department of Medicine, National Jewish Health, Denver, CO 80206, USA.
PMID: 19191632 DOI: 10.1086/597010
Abstract

Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.