Solophenols B-D and solomonin: new prenylated polyphenols isolated from propolis collected from the Solomon Islands and their antibacterial activity

  • J Agric Food Chem. 2012 Nov 28;60(47):11765-70. doi: 10.1021/jf303516w.
Saori Inui  1 ,  Takahiro Hosoya ,  Yuko Shimamura ,  Shuichi Masuda ,  Takeshi Ogawa ,  Hirokazu Kobayashi ,  Kenichi Shirafuji ,  Reuben Toli Moli ,  Ikuko Kozone ,  Kazuo Shin-ya ,  Shigenori Kumazawa
Affiliations
  • 1. Department of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.
PMID: 23067056 DOI: 10.1021/jf303516w
Abstract

Three new prenylated Flavonoids, namely, solophenols B (1), C (2), and D (3), as well as a new prenylated stilbene, solomonin (4), were isolated from propolis collected from the Solomon Islands. In addition, 17 known compounds were identified. The structures of the new compounds were determined by a combination of methods, including mass spectrometry and NMR. These new compounds and several known compounds were tested for Antibacterial activity against Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa. Most of them exhibited potent Antibacterial activity. These findings may indicate that propolis from the Solomon Islands has potential applications as an ingredient in food additives or pharmaceuticals.

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