Flavonol glycosides from the aerial parts of Gynostemma pentaphyllum and their antioxidant activity

  • Arch Pharm Res. 2016 Sep;39(9):1232-6. doi: 10.1007/s12272-016-0793-x.
Hari Jang  1 ,  Jin Woo Lee  1 ,  Chul Lee  1 ,  Qinghao Jin  1 ,  Myung Koo Lee  1 ,  Chong Kil Lee  1 ,  Mi Kyeong Lee  1 ,  Bang Yeon Hwang  2
Affiliations
  • 1. College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
  • 2. College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea. [email protected].
PMID: 27384065 DOI: 10.1007/s12272-016-0793-x
Abstract

The phytochemical investigation of the aerial parts of Gynostemma pentaphyllum led to the isolation of a new flavonol glycoside, gynopentaphylloside (1), along with seven known compounds (2-8). The structure of the new compound was determined on the basis of 1D, 2D NMR and HRESIMS data as well as acid hydrolysis. The antioxidant activity of the isolates was evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay.

Keywords
Antioxidant activity; Cucurbitaceae; Flavonol glycoside; Gynostemma pentaphyllum.
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