TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway

  • Signal Transduct Target Ther. 2020 Aug 25;5(1):163. doi: 10.1038/s41392-020-00276-7.
Huiyu Chen   #  1 ,  Yuhan Ye   #  2 ,  Yan Yang  1 ,  Mengya Zhong  1 ,  Lei Gu  3 ,  Zhaopu Han  1 ,  Jinhua Qiu  1 ,  Zhongchen Liu  4 ,  Xingfeng Qiu  5 ,  Guohong Zhuang  6  7
Affiliations
  • 1. Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China.
  • 2. Department of Pathology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian, China.
  • 3. Department of General Surgery, Shanghai 10th People's Hospital Affiliated to Tongji University, Shanghai, China.
  • 4. Department of General Surgery, Shanghai 10th People's Hospital Affiliated to Tongji University, Shanghai, China. [email protected].
  • 5. Department of Gastrointestinal Surgery, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian, China. [email protected].
  • 6. Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China. [email protected].
  • 7. Organ Transplantation Institute of Xiamen University, Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, Fujian, China. [email protected].
  • # Contributed equally.
PMID: 32843639 DOI: 10.1038/s41392-020-00276-7
Products