Serotonergic receptor antagonist from Nandina domestica Thunberg

  • J Pharm Sci. 1984 Apr;73(4):568-70. doi: 10.1002/jps.2600730435.
N Shoji ,  A Umeyama ,  T Takemoto ,  Y Ohizumi
PMID: 6726648 DOI: 10.1002/jps.2600730435
Abstract

A crude methanolic extract of the fruit of Nandina domestica Thunberg strongly inhibits serotonin-induced contractions of the rabbit aorta. The extract of the fruit has been fractionated to afford nantenine (O- methyldomesticine ) as the active agent.

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