Successful treatment of AIDS-related cryptosporidial sclerosing cholangitis

  • AIDS. 1993 Nov;7(11):1449-51. doi: 10.1097/00002030-199311000-00007.
A A Hamour  1 ,  A Bonnington ,  B Hawthorne ,  E G Wilkins
Affiliations
  • 1. Department of Infectious Diseases and Tropical Medicine, University of Manchester, UK.
PMID: 8280410 DOI: 10.1097/00002030-199311000-00007
Abstract

Objective: Cryptosporidium is a well recognized cause of AIDS-related sclerosing cholangitis for which no efficacious therapy exists at present. We evaluated the efficiency of the combination of paromomycin and letrazuril in the treatment of this condition.

Case report: We report a case of cryptosporidial cholangitis in a patient with AIDS who responded to treatment with intravenous paromomycin followed by oral letrazuril as maintenance therapy.

Conclusion: The combination of paromomycin and letrazuril should be considered in the treatment of AIDS-related sclerosing cholangitis.

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