R-75317
R-75317 is a specific platelet-activating factor (PAF) antagonist. R-75317 can prevent the decline in creatinine clearance (Ccr) in a rat model of glomerulonephritis induced by the injection of antibodies extracted from rabbits against rat glomerular basement membrane (GBM) antigens, delay the onset of proteinuria, and improve glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. R-75317 may be useful in the study of glomerulonephritis.
For research use only. We do not sell to patients.
- CAS No.: 115406-25-2
- Formula: C29H50N3O8PS
- Molecular Weight:631.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 115406-25-2
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Molecular Weight 631.76
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Formula C29H50N3O8PS
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SMILES
CCCCCCCCCCCCCCCCCNC(OC[C@@H](OC1=NOC=C1)COP(OCC[N+]2=CSC=C2)([O-])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)