(R)-GSK 2830371
Based on 1 Customer Validation
(R)-GSK 2830371 is the R-enantiomer of GSK 2830371 (HY-15832). GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 2743427-27-0
- Formula: C23H29ClN4O2S
- Molecular Weight:461.02
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2743427-27-0
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Appearance Solid
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Molecular Weight 461.02
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Formula C23H29ClN4O2S
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Color Off-white to light yellow
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SMILES
ClC1=CN=C(C)C(NCC2=CC=C(C(N[C@H](CC3CCCC3)C(NC4CC4)=O)=O)S2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (433.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1691 mL | 10.8455 mL | 21.6910 mL | 54.2276 mL |
| 5 mM | 0.4338 mL | 2.1691 mL | 4.3382 mL | 10.8455 mL | |
| 10 mM | 0.2169 mL | 1.0846 mL | 2.1691 mL | 5.4228 mL | |
| 15 mM | 0.1446 mL | 0.7230 mL | 1.4461 mL | 3.6152 mL | |
| 20 mM | 0.1085 mL | 0.5423 mL | 1.0846 mL | 2.7114 mL | |
| 25 mM | 0.0868 mL | 0.4338 mL | 0.8676 mL | 2.1691 mL | |
| 30 mM | 0.0723 mL | 0.3615 mL | 0.7230 mL | 1.8076 mL | |
| 40 mM | 0.0542 mL | 0.2711 mL | 0.5423 mL | 1.3557 mL | |
| 50 mM | 0.0434 mL | 0.2169 mL | 0.4338 mL | 1.0846 mL | |
| 60 mM | 0.0362 mL | 0.1808 mL | 0.3615 mL | 0.9038 mL | |
| 80 mM | 0.0271 mL | 0.1356 mL | 0.2711 mL | 0.6778 mL | |
| 100 mM | 0.0217 mL | 0.1085 mL | 0.2169 mL | 0.5423 mL |