rac-TNT-i
Based on 1 Customer Validation
rac-TNT-i (rac-NPD3064) is the racomer of TNT-i (HY-157469). TNT-i is an inhibitor targeting M-Sec. TNT-i reversibly inhibits the formation of tunnel nanotubes (TNT) induced by M-Sec. TNT-i can reduce the production of wild-type HIV-1 in macrophages and T cells expressing M-Sec. TNT-i has low cytotoxicity towards macrophages and T cells. TNT-i can be used in studies related to HIV-1 infection.
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- Formule: C18H25BrN2O2
- Masse moléculaire:381.31
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
Description
Chemical Information
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Appearance Solid
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Masse moléculaire 381.31
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Formule C18H25BrN2O2
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SMILES
OC1C2(CC)CN(CC1(CC)C3)C(C4=C(O)C=CC(Br)=C4)N3C2
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Synonyms
rac-NPD3064
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (131.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6225 mL | 13.1127 mL | 26.2254 mL | 65.5635 mL |
| 5 mM | 0.5245 mL | 2.6225 mL | 5.2451 mL | 13.1127 mL | |
| 10 mM | 0.2623 mL | 1.3113 mL | 2.6225 mL | 6.5563 mL | |
| 15 mM | 0.1748 mL | 0.8742 mL | 1.7484 mL | 4.3709 mL | |
| 20 mM | 0.1311 mL | 0.6556 mL | 1.3113 mL | 3.2782 mL | |
| 25 mM | 0.1049 mL | 0.5245 mL | 1.0490 mL | 2.6225 mL | |
| 30 mM | 0.0874 mL | 0.4371 mL | 0.8742 mL | 2.1854 mL | |
| 40 mM | 0.0656 mL | 0.3278 mL | 0.6556 mL | 1.6391 mL | |
| 50 mM | 0.0525 mL | 0.2623 mL | 0.5245 mL | 1.3113 mL | |
| 60 mM | 0.0437 mL | 0.2185 mL | 0.4371 mL | 1.0927 mL | |
| 80 mM | 0.0328 mL | 0.1639 mL | 0.3278 mL | 0.8195 mL | |
| 100 mM | 0.0262 mL | 0.1311 mL | 0.2623 mL | 0.6556 mL |