RBP4 inhibitor 1
Based on 1 Customer Validation
RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice.
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- Pureté : 99.49%
- CAS No.: 1198180-03-8
- Formule: C14H13F6NO3
- Masse moléculaire:357.25
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
IC50: 28 nM (human RBP4) and 110 nM (mouse RBP4)[1]
Chemical Information
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CAS No. 1198180-03-8
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Appearance Solid
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Masse moléculaire 357.25
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Formule C14H13F6NO3
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Color White to off-white
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SMILES
O=C(O)CO[C@@H]1CN(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 250 mg/mL (699.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7992 mL | 13.9958 mL | 27.9916 mL | 69.9790 mL |
| 5 mM | 0.5598 mL | 2.7992 mL | 5.5983 mL | 13.9958 mL | |
| 10 mM | 0.2799 mL | 1.3996 mL | 2.7992 mL | 6.9979 mL | |
| 15 mM | 0.1866 mL | 0.9331 mL | 1.8661 mL | 4.6653 mL | |
| 20 mM | 0.1400 mL | 0.6998 mL | 1.3996 mL | 3.4990 mL | |
| 25 mM | 0.1120 mL | 0.5598 mL | 1.1197 mL | 2.7992 mL | |
| 30 mM | 0.0933 mL | 0.4665 mL | 0.9331 mL | 2.3326 mL | |
| 40 mM | 0.0700 mL | 0.3499 mL | 0.6998 mL | 1.7495 mL | |
| 50 mM | 0.0560 mL | 0.2799 mL | 0.5598 mL | 1.3996 mL | |
| 60 mM | 0.0467 mL | 0.2333 mL | 0.4665 mL | 1.1663 mL | |
| 80 mM | 0.0350 mL | 0.1749 mL | 0.3499 mL | 0.8747 mL | |
| 100 mM | 0.0280 mL | 0.1400 mL | 0.2799 mL | 0.6998 mL |
RBP4 inhibitor 1 Related Classifications
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