Cadherin-3 Protein, Mouse (HEK293, His)

Cadherin-3 protein mediates cell-cell interactions by selectively binding to other cadherin molecules in a homophilic manner. This promotes adhesion between cells, aiding in the sorting and organization of different cell types. Cadherin-3 also interacts with CDCP1 and CTNNB1, regulating cellular processes and signaling pathways. Cadherin-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag.

Cadherin-3 protein, a calcium-dependent cell adhesion molecule, plays a crucial role in mediating cell-cell interactions. Through its ability to selectively interact with other cadherin molecules of the same type in a homophilic manner, Cadherin-3 facilitates the adhesion between connecting cells, thereby contributing to the sorting and organization of heterogeneous cell types in tissues and organs. In addition, Cadherin-3 interacts with CDCP1 and CTNNB1, further regulating cellular processes and signaling pathways.

Mouse

HEK293

C-8*His

P10287 (E100-G647)

12560  [NCBI]

Extracellular Domain

EWVMPPIFVPENGKGPFPQRLNQLKSNKDRGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNSPAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVVHVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDKEDQKISYTISRDPANWLAVDPDSGQITAAGILDREDEQFVKNNVYEVMVLATDSGNPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVFNDCPRPWKGG

70-80 kDa

≥ 90%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.