Cadherin-6/KCAD Protein, Mouse (HEK293, His)
Cadherin-6/KCAD protein acts as a calcium-dependent cell adhesion protein and mediates cell-cell interactions. They preferentially interact in the same way with other cadherin molecules of the same type, promoting adhesion between cells. Cadherin-6/KCAD Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Cadherin-6/KCAD protein acts as a calcium-dependent cell adhesion protein and mediates cell-cell interactions. They preferentially interact in the same way with other cadherin molecules of the same type, promoting adhesion between cells. Cadherin-6/KCAD Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag.
Background
Cadherin-6/KCAD protein is a calcium-dependent cell adhesion protein that plays a crucial role in mediating cell-cell interactions. It exhibits a preference for interacting with other cadherin molecules of the same type in a homophilic manner, facilitating the adhesion between connecting cells. This unique ability of cadherins to selectively interact with themselves contributes to the sorting and organization of heterogeneous cell types in tissues and organs. As a calcium-dependent adhesion protein, Cadherin-6/KCAD participates in maintaining the structural integrity of tissues and regulating cellular processes such as development, differentiation, and morphogenesis.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-His
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Accession
P97326 (T19-A615)
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Molecular Construction
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N-term
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CDH6 (T19-A615)
Accession # P97326 -
His
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C-term
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Protein Length
Extracellular Domain (with propeptide)
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Synonyms
CDH6; Alternative Protein CDH6; Cadherin 6; Kidney Cadherin; Cadherin 6, Type 2, K-Cadherin (Fetal Kidney); CAD6; K-Cadherin; KCAD; Cadherin-6
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AA Sequence
TFSNPLSKRTSGFPAKRKALELSANSRNELSRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAVNRRTGRPVEPESEFIIKIHDINDNEPIFTKDVYTATVPEMADVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGHEMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPHVEPRFLYLGPFKDSATVRIVVDDVDEPPVFSKLAYILQIREDARINTTIGSVAAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLRAVDKDDPYSGHQFSFSLAPEAASSSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGA
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Predicted Molecular Mass
68.7 kDa
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Molecular Weight
Approximately 80-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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