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CNTN4/Contactin-4 Protein, Mouse (sf9, His)

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CNTN4/Contactin-4 protein mediates cell surface interactions in nervous system development and promotes neurite outgrowth. Its involvement in synaptogenesis highlights its significance in shaping neural connectivity. CNTN4 also interacts with PTPRG, potentially regulating neuronal functions and synaptic development. CNTN4/Contactin-4 Protein, Mouse (sf9, His) is the recombinant mouse-derived CNTN4/Contactin-4 protein, expressed by Sf9 insect cells , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Mouse
  • Source: Sf9 insect cells
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • CNTN4/Contactin-4 Protein, Mouse (sf9, His) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
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Biological Activity

Description

CNTN4/Contactin-4 protein mediates cell surface interactions in nervous system development and promotes neurite outgrowth. Its involvement in synaptogenesis highlights its significance in shaping neural connectivity. CNTN4 also interacts with PTPRG, potentially regulating neuronal functions and synaptic development. CNTN4/Contactin-4 Protein, Mouse (sf9, His) is the recombinant mouse-derived CNTN4/Contactin-4 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Background

Contactin-4 (CNTN4) serves a crucial role in mediating cell surface interactions during nervous system development. With its neurite outgrowth-promoting activity, CNTN4 contributes to the intricate processes of synaptogenesis. The protein's involvement in promoting neurite extension emphasizes its potential significance in shaping neural connectivity. Additionally, CNTN4 interacts with protein tyrosine phosphatase receptor gamma (PTPRG), suggesting a molecular partnership that may play a role in regulating neuronal functions and synaptic development.

Technical Parameters

  • Species Mouse
  • Source Sf9 insect cells
  • Tag C-His
  • Accession

    Q69Z26-1 (D19-G999)

  • Gene ID
    269784  [NCBI]
  • Molecular Construction
    • N-term
    • CNTN4 (D19-G999)
      Accession # Q69Z26-1
    • His
    • C-term
  • Protein Length

    Partial

  • Synonyms

    CNTN4; Contactin-4; Contactin 4; Axonal-Associated Cell Adhesion Molecule; BIG-2; Neural Cell Adhesion Protein BIG-2; Brain-Derived Immunoglobulin Superfamily Protein 2; AXCAM

  • AA Sequence

    DDYTLHGPVFVQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKINGTDVDIGMDFRYSVVDGSLLINNPNKTQDAGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPAEKGTTVKLECFALGNPVPTILWRRADGKPIARKARRHKSNGILEIPNFQQEDAGSYECVAENSRGKNVAKGQLTFYAQPNWVQIINDIHVAMEESVFWECKANGRPKPTYRWLKNGDPLLTRDRIQIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAESPDFSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNVIVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSVAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPDLVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFARSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENAKKIRTVGNQTSTKITNLKGSALYHLSVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNSYARG

  • Predicted Molecular Mass

    110.2 kDa

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 8.0
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

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Dilution Calculator

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
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Biological Activity (ED50) Biological Activity (ED50)
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ng/mL
MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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