Contactin-4
Contactin-4 (CNTN4) is a GPI-anchored member of the contactin subfamily expressed predominantly in the brain, with high levels during neuronal development. It mediates neurite outgrowth and heterophilic adhesion, and has been shown to interact with receptor protein tyrosine phosphatases and with the amyloid precursor protein pathway. Deletions and disruptive variants within CNTN4 on chromosome 3p26 are among the recurrent copy-number changes in autism spectrum disorder and intellectual disability, and the gene sits near the region deleted in 3p- syndrome. These genetics position recombinant CNTN4 as a tool for neurodevelopmental disorder research and antibody-based detection.
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Contactin-4 Recombinant Proteins (2)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
