2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Hydrolases (EC 3) Phosphatase
  5. ENPP-3 Protein, Canine (HEK293, His)

ENPP-3 Protein, Canine (HEK293, His)

Cat. No.: HY-P700710
Handling Instructions

ENPP-3 is a hydrolase that plays a crucial role in regulating the immune response. ENPP-3 plays an important role in tumor development and invasion. The hypomethylation of the ENPP-3 promoter region is involved in the occurrence and progression of ovarian endometriosis through the AKT/mTOR/4EBP1 signaling pathway. ENPP-3 Protein, Canine (HEK293, His) is the recombinant canine-derived ENPP-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of ENPP-3 Protein, Canine (HEK293, His) is 829 a.a., with molecular weight of 110-130 kDa.

For research use only. We do not sell to patients.

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Description

ENPP-3 is a hydrolase that plays a crucial role in regulating the immune response. ENPP-3 plays an important role in tumor development and invasion. The hypomethylation of the ENPP-3 promoter region is involved in the occurrence and progression of ovarian endometriosis through the AKT/mTOR/4EBP1 signaling pathway. ENPP-3 Protein, Canine (HEK293, His) is the recombinant canine-derived ENPP-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of ENPP-3 Protein, Canine (HEK293, His) is 829 a.a., with molecular weight of 110-130 kDa.
Background

ENPP-3 is a hydrolase with the ability to metabolize a variety of extracellular nucleotides, including ATP, GTP, UTP, and CTP. This enzyme activity plays a crucial role in regulating the immune response, especially during the chronic stages of inflammation and allergic reactions. ENPP-3 is a protein detected in the womb that plays an important role in tumor development and invasion. The hypomethylation of the ENPP-3 promoter region is involved in the occurrence and progression of ovarian endometriosis through the AKT/mTOR/4EBP1 signaling pathway[1][2][3].
Species

Canine
Source

HEK293
Tag

N-His
Accession

A0A8I3N0F5 (R46-I874)
Gene ID

/
Molecular Construction
N-term
His
ENPP-3 (R46-I874)
Accession # A0A8I3N0F5
C-term
Synonyms
E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6; PD-Iβ
Molecular Weight

110-130 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

ENPP-3 Protein, Canine (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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