1. Recombinant Proteins
  2. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  3. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  4. Eph Receptors
  5. EphA10
  6. EPHA10 Protein, Cynomolgus (HEK293, His)

EPHA10 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700711
Handling Instructions

EphA10, a receptor for ephrin-A family members, selectively binds EFNA3, EFNA4, and EFNA5, indicating its involvement in mediating cellular responses to ephrin-A ligands and participating in diverse cellular processes regulated by Eph-ephrin signaling pathways. EPHA10 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag. The total length of EPHA10 Protein, Cynomolgus (HEK293, His) is 532 a.a., with molecular weight of 68-78 kDa.

For research use only. We do not sell to patients.

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Description

EphA10, a receptor for ephrin-A family members, selectively binds EFNA3, EFNA4, and EFNA5, indicating its involvement in mediating cellular responses to ephrin-A ligands and participating in diverse cellular processes regulated by Eph-ephrin signaling pathways. EPHA10 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag. The total length of EPHA10 Protein, Cynomolgus (HEK293, His) is 532 a.a., with molecular weight of 68-78 kDa.

Background

EphA10, identified as a receptor for members of the ephrin-A family, plays a crucial role in cellular signaling. Specifically, it acts as a receptor for ephrin ligands EFNA3, EFNA4, and EFNA5. The interaction between EphA10 and these ephrin-A family members suggests its involvement in diverse cellular processes, likely including cell-cell communication and regulation of tissue development. This receptor-ligand binding capacity highlights EphA10's significance in mediating signaling events that contribute to various physiological and developmental processes.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

XP_045230088.1 (E34-A565)

Gene ID

102120465  [NCBI]

Molecular Construction
N-term
EPHA10 (E34-A565)
Accession # XP_045230088.1
His
C-term
Synonyms
EphA10; FLJ16103; FLJ33655; MGC43817
Molecular Weight

68-78 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
EPHA10 Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P700711
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