GJD2 Protein, Bovine (Cell-Free, His, SUMO)

GJD2 Protein, a connexin, aids in gap junction formation, where connexons create transmembrane channels. These channels allow direct intercellular communication by facilitating the diffusion of low molecular weight materials between adjacent cells. Each hexameric connexon, composed of connexins, plays a crucial role in exchanging essential substances among neighboring cells within gap junction clusters. GJD2 Protein, Bovine (Cell-Free, His, SUMO) is the recombinant bovine-derived GJD2 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of GJD2 Protein, Bovine (Cell-Free, His, SUMO) is 321 a.a., with molecular weight of 49.1 kDa.

GJD2 Protein, as a connexin, contributes to the formation of gap junctions, which comprise closely packed pairs of transmembrane channels known as connexons. These connexons facilitate the diffusion of low molecular weight materials from one cell to an adjacent cell, enabling direct intercellular communication. Each connexon is constructed as a hexamer of connexins, and these intricate structures play a crucial role in the exchange of essential substances between neighboring cells within the cluster of gap junctions.

Bovine

E. coli Cell-free

N-6*His;N-SUMO

Q866T7 (M1-V321)

282577

MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPESMGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRTASRSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECDRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSVYEIRNKDLPRVSVPNFGRTQSSDSAYV

49.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.