MASP2 Protein, Mouse (His)

MASP2 Protein, a serum protease, plays a pivotal role in activating the complement system by cleaving C2 and C4 upon auto-catalytic cleavage. This activation leads to the formation of C3 convertase, a crucial step in initiating the complement cascade through mannose-binding lectin. MASP2 Protein, Mouse (His) is the recombinant mouse-derived MASP2 protein, expressed by E. coli , with C-His labeled tag. The total length of MASP2 Protein, Mouse (His) is 399 a.a., with molecular weight of 18-20 kDa.

MASP2 is a serum protease crucial for the activation of the complement system through mannose-binding lectin. Upon auto-catalytic cleavage, MASP2 effectively cleaves C2 and C4, resulting in their activation and subsequent formation of C3 convertase, which is vital for the complement cascade.

Mouse

E. coli

C-His

Q91WP0 (T287-F685)

17175  [NCBI]

18-20 kDa

Greater than 95% as determined by Tris-Bis PAGE

<1 EU/μg, determined by LAL method.