Masp2 - mannan-binding lectin serine peptidase 2 Gene

Also Known as MAp19; MASP-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17175

Summary

Predicted to enable several functions, including calcium-dependent protein binding activity; complement component C4b binding activity; and serine-type endopeptidase activity. Acts upstream of or within complement activation, lectin pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain and liver. Orthologous to human MASP2 (MBL associated serine protease 2). [provided by Alliance of Genome Resources, Apr 2022]

Masp2 Products (2)

mRNA Protein Name
NM_001003893.2 NP_001003893.1 mannan-binding lectin serine protease 2 isoform 1 precursor
NM_010767.3 NP_034897.1 mannan-binding lectin serine protease 2 isoform 2 precursor
Protein Preferred Names Protein Names

mannan-binding lectin serine protease 2

  • MBL-associated serine protease 2

  • mannose-binding protein-associated serine protease 2

Recombinant Masp2 Proteins

Cat. No. Product Name Accession Purity
HY-P77800 MASP2 Protein, Mouse (His) Q91WP0 (T287-F685) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99376 Narsoplimab Inhibitor ≥99.0% Unkown

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991312 CM-338 Inhibitor 97.93% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0227 SHU 9119 99.83% Unkown
HY-P1208 PG-931 Agonist 99.60% Unkown
HY-172090 MASP-2-IN-1 Inhibitor / Unkown
HY-E70390 C1s Enzyme Antagonist / Unkown
HY-RS08160 MASP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17231 Masp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23684 Masp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992463 SHR-2010 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Masp2 NCBI NCBI:10747