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  4. MFAP4 Protein, Cynomolgus (HEK293, His)

MFAP4 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700873
Handling Instructions

MFAP4 is part of the microfibril-associated glycoprotein (MFAP) family and is involved in cell adhesion, cell-cell interactions, and the assembly and/or maintenance of elastic fibers. MFAP4 deficiency alleviates renal fibrosis by inhibiting NF-κB and TGF-β/Smad signaling pathways. MFAP4 is a novel biomarker for human cancer. MFAP4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MFAP4 protein, expressed by HEK293 , with C-His labeled tag. The total length of MFAP4 Protein, Cynomolgus (HEK293, His) is 234 a.a., with molecular weight of 35-40 kDa.

For research use only. We do not sell to patients.

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Description

MFAP4 is part of the microfibril-associated glycoprotein (MFAP) family and is involved in cell adhesion, cell-cell interactions, and the assembly and/or maintenance of elastic fibers. MFAP4 deficiency alleviates renal fibrosis by inhibiting NF-κB and TGF-β/Smad signaling pathways. MFAP4 is a novel biomarker for human cancer. MFAP4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MFAP4 protein, expressed by HEK293 , with C-His labeled tag. The total length of MFAP4 Protein, Cynomolgus (HEK293, His) is 234 a.a., with molecular weight of 35-40 kDa.
Background

MFAP4 is part of the microfibril-associated glycoprotein (MFAP) family and is involved in cell adhesion, cell-cell interactions, and the assembly and/or maintenance of elastic fibers. MFAP4 deficiency alleviates renal fibrosis by inhibiting NF-κB and TGF-β/Smad signaling pathways. MFAP4 can promote the migration and proliferation of vascular smooth muscle and accelerate the formation of new intima. MFAP4 could also serve as a novel biomarker for the development of human cancer therapies[1][2][3].
Species

Cynomolgus
Source

HEK293
Tag

C-His
Accession

A0A2K5TQS8 (V60-A293)
Gene ID

/
Molecular Construction
N-term
MFAP4 (V60-A293)
Accession # A0A2K5TQS8
His
C-term
Synonyms
Microfibril-associated glycoprotein 4; Mfap4
Molecular Weight

35-40 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

MFAP4 Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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