Neurocalcin-delta/NCALD Protein, Human (His)
Neurocalcin-delta/NCALD proteins are involved in calcium-dependent regulation of rhodopsin phosphorylation, affecting dynamics critical for visual signal transduction. NCALD is capable of binding three calcium ions and is important in calcium-mediated pathways that control photoreceptor function. Neurocalcin-delta/NCALD Protein, Human (His) is the recombinant human-derived Neurocalcin-delta/NCALD protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Neurocalcin-delta/NCALD proteins are involved in calcium-dependent regulation of rhodopsin phosphorylation, affecting dynamics critical for visual signal transduction. NCALD is capable of binding three calcium ions and is important in calcium-mediated pathways that control photoreceptor function. Neurocalcin-delta/NCALD Protein, Human (His) is the recombinant human-derived Neurocalcin-delta/NCALD protein, expressed by E. coli , with N-6*His labeled tag.
Background
Neurocalcin-delta/NCALD Protein surfaces as a potential participant in the intricacies of calcium-dependent regulation of rhodopsin phosphorylation, highlighting its role in modulating the phosphorylation dynamics crucial for visual signal transduction. With the capacity to bind three calcium ions, NCALD underscores its significance in calcium-mediated pathways governing photoreceptor function. The interaction with GUCY2D further suggests its involvement in molecular networks related to visual signal processing. Unraveling the specific mechanisms by which NCALD contributes to rhodopsin phosphorylation and its interplay with calcium signaling may offer valuable insights into the regulatory processes shaping visual sensitivity and adaptation. Exploring the functional implications of NCALD in the context of calcium-dependent rhodopsin regulation could enhance our understanding of its role in maintaining the integrity of visual signaling pathways.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
P61601 (M1-F193)
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Molecular Construction
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N-term
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6*His
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NCALD (M1-F193)
Accession # P61601 -
C-term
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Protein Length
Full Length
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Synonyms
NCALD; Neurocalcin-Delta; Neurocalcin Delta
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AA Sequence
MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF
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Predicted Molecular Mass
24.4 kDa
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Molecular Weight
Approximately 25 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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