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  3. Receptor Proteins
  4. NKp46/NCR1 Protein, Mouse (HEK293, His)

NKp46/NCR1 Protein, Mouse (HEK293, His)

Cat. No.: HY-P78331
Handling Instructions

NKp46/NCR1 Protein, a cytotoxicity-activating receptor, boosts activated natural killer (NK) cells' efficacy in eliminating tumor cells. Its interaction with CD3Z and FCER1G suggests a potential role in aiding NK cells in recognizing and destroying cancerous cells. NKp46/NCR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NKp46/NCR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NKp46/NCR1 Protein, Mouse (HEK293, His) is 234 a.a., with molecular weight of 45-60 kDa.

For research use only. We do not sell to patients.

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Description

NKp46/NCR1 Protein, a cytotoxicity-activating receptor, boosts activated natural killer (NK) cells' efficacy in eliminating tumor cells. Its interaction with CD3Z and FCER1G suggests a potential role in aiding NK cells in recognizing and destroying cancerous cells. NKp46/NCR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NKp46/NCR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NKp46/NCR1 Protein, Mouse (HEK293, His) is 234 a.a., with molecular weight of 45-60 kDa.
Background

NKp46/NCR1 Protein is a cytotoxicity-activating receptor that enhances the effectiveness of activated natural killer (NK) cells in killing tumor cells. It interacts with CD3Z and FCER1G, potentially aiding in the recognition and destruction of cancerous cells by NK cells.
Species

Mouse
Source

HEK293
Tag

C-His
Accession

Q8C567 (E22-N255)
Gene ID

17086  [NCBI]
Molecular Construction
N-term
NKp46 (E22-N255)
Accession # Q8C567
His
C-term
Synonyms
CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
Molecular Weight

45-60 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NKp46/NCR1 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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