Ncr1 - natural cytotoxicity triggering receptor 1 Gene

Also Known as Ly94; NKp46

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17086

Summary

Acts upstream of or within defense response to virus and detection of virus. Located in cell surface. Orthologous to human NCR1 (natural cytotoxicity triggering receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncr1 Products (2)

mRNA Protein Name
NM_001368364.1 NP_001355293.1 natural cytotoxicity triggering receptor 1 isoform 2
NM_010746.3 NP_034876.2 natural cytotoxicity triggering receptor 1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28480349 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within defense response to virus IMP
IMP: Inferred from mutant phenotype
22615821 MGI
acts upstream of or within detection of virus IMP
IMP: Inferred from mutant phenotype
22615821 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
20818394 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

natural cytotoxicity triggering receptor 1

  • MAR1 (mouse activating receptor 1)

  • NK-p46

  • activating receptor 1

  • lymphocyte antigen 94

  • mAR-1

  • mNKp46

  • natural killer cell p46-related protein

Recombinant Ncr1 Proteins

Cat. No. Product Name Accession Purity
HY-P70562 NKp46/NCR1 Protein, Mouse (HEK293, Fc) Q8C567 (E22-N255) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P78331 NKp46/NCR1 Protein, Mouse (HEK293, His) Q8C567 (E22-N255) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P78831 NKp46/NCR1 Protein, Mouse (Biotinylated, HEK293, His-Avi) Q8C567 (E22-N255) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990905 Bexatamig Inhibitor 97.06% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09098 NCR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17588 Ncr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24048 Ncr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991326 BL-9020 Inhibitor 98.32% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncr1 NCBI NCBI:9437