PEX11A Protein, Human (HEK293, Fc)

The PEX11A protein may regulate peroxisome dynamics, affecting peroxisome proliferation and division by promoting the association of coating proteins with the peroxisomal membrane. PEX11A is associated with structural organization and promotes membrane protrusion and elongation at the peroxisomal surface. PEX11A Protein, Human (HEK293, Fc) is the recombinant human-derived PEX11A protein, expressed by HEK293 , with N-mFc labeled tag. The total length of PEX11A Protein, Human (HEK293, Fc) is 114 a.a., with molecular weight of ~40 KDa.

PEX11A Protein emerges as a potential regulator in peroxisomal dynamics, playing a role in peroxisomal proliferation and contributing to the regulation of peroxisome division. It may facilitate the binding of coatomer proteins to the peroxisomal membrane, suggesting involvement in the structural organization of these cellular organelles. Additionally, PEX11A is implicated in promoting membrane protrusion and elongation on the peroxisomal surface. Existing as a homodimer and forming a heterodimer with PEX11G, PEX11A likely engages in complex interactions to influence peroxisomal functions. Potential interactions with COPB2, COPA, PEX19, and FIS1 further underscore the intricate network of associations in which PEX11A is involved, hinting at its multifaceted role in peroxisomal biology. Delving deeper into the specific mechanisms governing PEX11A's contributions to peroxisomal dynamics could provide valuable insights into its role in cellular homeostasis and metabolism.

Human

HEK293

N-mFc

O75192 (R106-P219)

8800  [NCBI]

Approximately 40 kDa.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.